与此同时，研发投入在千万元及以上区间的企业数量，已经连续五年保持两位数的增长，反映出更多企业正在系统化、规模化地投入研发活动。
While Illumina ultimately opted for a method that simultaneously detected massive numbers of DNA strands, others still believed that single-molecule sequencing methods offered a better path forward. Sequencing by synthesis requires repeated amplification, which introduces the possibility of error at each step and biases outputs towards sequences readily amplified by DNA polymerase. Single-molecule techniques were billed as a way to sequence DNA with minimal bias while simultaneously reducing cost.
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